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Mouse ADP-ribosylation factor-like protein 2 (aa 1-184 )

Arl2 Swiss Prot#

Q9D0J4

Arl2 Protein names

ADP-ribosylation factor-like protein 2

Arl2 Gene names

Arl2

Organism

Mus musculus (Mouse)

Arl2 Entry name

ARL2_MOUSE

Arl2 Codon optimized cDNA(gene) Clone

Arl2 Cat #

RPY0227

Tag

Arl2 contains A 6x histidine tag

Arl2 Formulation

Liquid

Arl2 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Arl2 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Arl2 Protein

Arl2 Cat #

PY0227

Arl2 Source

recombinant

Arl2 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Arl2 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Arl2 Activity

N/A

Tag

Arl2 Contains A 6x histidine tag

Arl2 Formulation

Liquid

Arl2 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Arl2 family

Small GTPase superfamily, Arf family

Arl2 Subcellular locations

Mitochondrion intermembrane space. Cytoplasm > cytoskeleton > centrosome. Nucleus. Cytoplasm.

Arl2 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Regulates formation of new microtubules and centrosome integrity. Prevents the TBCD-induced microtubule destruction. Participates in association with TBCD, in the disassembly of the apical junction complexes. Antagonizes the effect of TBCD on epithelial cell detachment and tight and adherens junctions disassembly. Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. Component of a regulated secretory pathway involved in Ca(2+)-dependent release of acetylcholine. Required for normal progress through the cell cycle.

Arl2 Sequence

DDBJ

EMBL

GenBank

Arl2 3D structure

ModBase

Arl2 interaction

STRING

Arl2 Proteomic

PRIDE

Arl2 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Arl2 Organism specific

CTD

MGI

Arl2 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Arl2 Gene expression

Bgee

ArrayExpress

Genevestigator

Arl2 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY