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Human Podoplanin (aa 21-162 )

GP36 Swiss Prot#

Q86YL7

GP36 Protein names

Podoplanin (Aggrus) (Glycoprotein 36) (Gp36) (PA2.26 antigen) (T1-alpha) (T1A)

GP36 Gene names

PDPN GP36 PSEC0003 PSEC0025

Organism

Homo sapiens (Human)

GP36 Entry name

PDPN_HUMAN

GP36 Codon optimized cDNA(gene) Clone

GP36 Cat #

RPY0154

Tag

GP36 contains A 6x histidine tag

GP36 Formulation

Liquid

GP36 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

GP36 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant GP36 Protein

GP36 Cat #

PY0154

GP36 Source

recombinant

GP36 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

GP36 Purity

>90%, as determined by SDS-PAGE under reducing conditions

GP36 Activity

N/A

Tag

GP36 Contains A 6x histidine tag

GP36 Formulation

Liquid

GP36 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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GP36 family

Podoplanin family

GP36 Subcellular locations

Membrane; Single-pass type I membrane protein. Cell projection > filopodium membrane; Single-pass type I membrane protein. Cell projection > lamellipodium membrane; Single-pass type I membrane protein. Cell projection > microvillus membrane; Single-pass type I membrane protein. Cell projection > ruffle membrane; Single-pass type I membrane protein.

GP36 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: May be involved in cell migration and/or actin cytoskeleton organization. When expressed in keratinocytes, induces changes in cell morphology with transfected cells showing an elongated shape, numerous membrane protrusions, major reorganization of the actin cytoskeleton, increased motility and decreased cell adhesion. Required for normal lung cell proliferation and alveolus formation at birth. Induces platelet aggregation. Does not have any effect on folic acid or amino acid transport. Does not function as a water channel or as a regulator of aquaporin-type water channels.

GP36 Sequence

DDBJ

EMBL

GenBank

GP36 3D structure

ModBase

GP36 interaction

STRING

GP36 Proteomic

PRIDE

GP36 Genome annotation

Ensembl

GeneID

KEGG

UCSC

GP36 Organism specific

CTD

MGI

GP36 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

GP36 Gene expression

Bgee

ArrayExpress

Genevestigator

GP36 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY