|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
|
||||||||||||||||||||||||||||||||||
|
|||||||||||||
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Mouse Baculoviral IAP repeat-containing protein 5 (aa 1-140 ) |
| Birc5 Swiss Prot# | | O70201 |
| Birc5 Protein names | | Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor 4) (Apoptosis inhibitor survivin) (TIAP) |
| Birc5 Gene names | | Birc5 Api4 Iap4 |
| Organism | | Mus musculus (Mouse) |
| Birc5 Entry name | | BIRC5_MOUSE |
| Birc5 Codon optimized cDNA(gene) Clone |
| Birc5 Cat # | | RPY0099 |
| Tag | | Birc5 contains A 6x histidine tag |
| Birc5 Formulation | | Liquid |
| Birc5 Storage | | Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Birc5 Applications | | Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function. |
| Recombinant Birc5 Protein |
| Birc5 Cat # | | PY0099 |
| Birc5 Source | | recombinant |
| Birc5 Applications | | Western Blot, SDS-Page or may be used for other applications determined by user |
| Birc5 Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| Birc5 Activity | | N/A |
| Tag | | Birc5 Contains A 6x histidine tag |
| Birc5 Formulation | | Liquid |
| Birc5 Storage | | ;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant Birc5 Products | | For pricing and availability Click Here >>> |
| Birc5 family | | IAP family |
| Birc5 Subcellular locations | | Cytoplasm. Nucleus. Chromosome > centromere. Cytoplasm > cytoskeleton > spindle. |
| Birc5 FUNCTION According to UniProtKB Swiss Prot | | FUNCTION: Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. The complex with RAN plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules. May play a role in neoplasia. May counteract a default induction of apoptosis in G2/M phase. Inhibitor of caspase-3 and caspase-7 (By similarity). |
| Birc5 Sequence | | DDBJ | EMBL | GenBank |
| Birc5 3D structure | | ModBase |
| Birc5 interaction | | STRING |
| Birc5 Proteomic | | PRIDE |
| Birc5 Genome annotation | | Ensembl | GeneID | KEGG | UCSC |
| Birc5 Organism specific | | CTD | MGI |
| Birc5 Phylogenomics | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| Birc5 Gene expression | | Bgee | ArrayExpress | Genevestigator |
| Birc5 Family and domain | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |