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Mouse Baculoviral IAP repeat-containing protein 5 (aa 1-140 )
Birc5 Swiss Prot#
O70201
Birc5 Protein names
Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor 4) (Apoptosis inhibitor survivin) (TIAP)
Birc5 Gene names
Birc5 Api4 Iap4
Organism
Mus musculus (Mouse)
Birc5 Entry name
BIRC5_MOUSE
Birc5 Codon optimized cDNA(gene) Clone
Birc5 Cat #
RPY0099
Tag
Birc5 contains A 6x histidine tag
Birc5 Formulation
Liquid
Birc5 Storage
Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
Birc5 Applications
Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant Birc5 Protein
Birc5 Cat #
PY0099
Birc5 Source
recombinant
Birc5 Applications
Western Blot, SDS-Page or may be used for other applications determined by user
Birc5 Purity
>90%, as determined by SDS-PAGE under reducing conditions
Birc5 Activity
N/A
Tag
Birc5 Contains A 6x histidine tag
Birc5 Formulation
Liquid
Birc5 Storage
;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant Birc5 Products
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Birc5 family
IAP family
Birc5 Subcellular locations
Cytoplasm. Nucleus. Chromosome > centromere. Cytoplasm > cytoskeleton > spindle.
Birc5 FUNCTION According to UniProtKB Swiss Prot
FUNCTION: Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. The complex with RAN plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules. May play a role in neoplasia. May counteract a default induction of apoptosis in G2/M phase. Inhibitor of caspase-3 and caspase-7 (By similarity).
Birc5 Sequence
DDBJ EMBL GenBank
Birc5 3D structure
ModBase
Birc5 interaction
STRING
Birc5 Proteomic
PRIDE
Birc5 Genome annotation
Ensembl GeneID KEGG UCSC
Birc5 Organism specific
CTD MGI
Birc5 Phylogenomics
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
Birc5 Gene expression
Bgee ArrayExpress Genevestigator
Birc5 Family and domain
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY