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Human Dynein light chain 1 cytoplasmic (aa 1-89 )
DYNLL1 Swiss Prot#
P63167
DYNLL1 Protein names
Dynein light chain 1, cytoplasmic (8 kDa dynein light chain) (DLC8) (Dynein light chain LC8-type 1) (Protein inhibitor of neuronal nitric oxide synthase) (PIN)
DYNLL1 Gene names
DYNLL1 DLC1 DNCL1 DNCLC1 HDLC1
Organism
Homo sapiens (Human)
DYNLL1 Entry name
DYL1_HUMAN
DYNLL1 Codon optimized cDNA(gene) Clone
DYNLL1 Cat #
RPY0012
Tag
DYNLL1 contains A 6x histidine tag
DYNLL1 Formulation
Liquid
DYNLL1 Storage
Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
DYNLL1 Applications
Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant DYNLL1 Protein
DYNLL1 Cat #
PY0012
DYNLL1 Source
recombinant
DYNLL1 Applications
Western Blot, SDS-Page or may be used for other applications determined by user
DYNLL1 Purity
>90%, as determined by SDS-PAGE under reducing conditions
DYNLL1 Activity
N/A
Tag
DYNLL1 Contains A 6x histidine tag
DYNLL1 Formulation
Liquid
DYNLL1 Storage
;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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DYNLL1 family
Dynein light chain family
DYNLL1 Subcellular locations
Cytoplasm > cytoskeleton. Nucleus. Mitochondrion.
DYNLL1 FUNCTION According to UniProtKB Swiss Prot
FUNCTION: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.; FUNCTION: Binds and inhibits the catalytic activity of neuronal nitric oxide synthase.; FUNCTION: Promotes transactivation functions of ESR1 and plays a role in the nuclear localization of ESR1.; FUNCTION: Regulates apoptotic activities of BCL2L11 by sequestering it to microtubules. Upon apoptotic stimuli the BCL2L11-DYNLL1 complex dissociates from cytoplasmic dynein and translocates to mitochondria and sequesters BCL2 thus neutralizing its antiapoptotic activity.
DYNLL1 Sequence
DDBJ EMBL GenBank
DYNLL1 3D structure
ModBase
DYNLL1 interaction
STRING
DYNLL1 Proteomic
PRIDE
DYNLL1 Genome annotation
Ensembl GeneID KEGG UCSC
DYNLL1 Organism specific
CTD MGI
DYNLL1 Phylogenomics
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
DYNLL1 Gene expression
Bgee ArrayExpress Genevestigator
DYNLL1 Family and domain
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY