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| Human Dynein light chain 1 cytoplasmic (aa 1-89 ) |
| DYNLL1 Swiss Prot# | | P63167 |
| DYNLL1 Protein names | | Dynein light chain 1, cytoplasmic (8 kDa dynein light chain) (DLC8) (Dynein light chain LC8-type 1) (Protein inhibitor of neuronal nitric oxide synthase) (PIN) |
| DYNLL1 Gene names | | DYNLL1 DLC1 DNCL1 DNCLC1 HDLC1 |
| Organism | | Homo sapiens (Human) |
| DYNLL1 Entry name | | DYL1_HUMAN |
| DYNLL1 Codon optimized cDNA(gene) Clone |
| DYNLL1 Cat # | | RPY0012 |
| Tag | | DYNLL1 contains A 6x histidine tag |
| DYNLL1 Formulation | | Liquid |
| DYNLL1 Storage | | Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| DYNLL1 Applications | | Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function. |
| Recombinant DYNLL1 Protein |
| DYNLL1 Cat # | | PY0012 |
| DYNLL1 Source | | recombinant |
| DYNLL1 Applications | | Western Blot, SDS-Page or may be used for other applications determined by user |
| DYNLL1 Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| DYNLL1 Activity | | N/A |
| Tag | | DYNLL1 Contains A 6x histidine tag |
| DYNLL1 Formulation | | Liquid |
| DYNLL1 Storage | | ;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant DYNLL1 Products | | For pricing and availability Click Here >>> |
| DYNLL1 family | | Dynein light chain family |
| DYNLL1 Subcellular locations | | Cytoplasm > cytoskeleton. Nucleus. Mitochondrion. |
| DYNLL1 FUNCTION According to UniProtKB Swiss Prot | | FUNCTION: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.; FUNCTION: Binds and inhibits the catalytic activity of neuronal nitric oxide synthase.; FUNCTION: Promotes transactivation functions of ESR1 and plays a role in the nuclear localization of ESR1.; FUNCTION: Regulates apoptotic activities of BCL2L11 by sequestering it to microtubules. Upon apoptotic stimuli the BCL2L11-DYNLL1 complex dissociates from cytoplasmic dynein and translocates to mitochondria and sequesters BCL2 thus neutralizing its antiapoptotic activity. |
| DYNLL1 Sequence | | DDBJ | EMBL | GenBank |
| DYNLL1 3D structure | | ModBase |
| DYNLL1 interaction | | STRING |
| DYNLL1 Proteomic | | PRIDE |
| DYNLL1 Genome annotation | | Ensembl | GeneID | KEGG | UCSC |
| DYNLL1 Organism specific | | CTD | MGI |
| DYNLL1 Phylogenomics | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| DYNLL1 Gene expression | | Bgee | ArrayExpress | Genevestigator |
| DYNLL1 Family and domain | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |