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Rat V-set domain-containing T-cell activation inhibitor 1 (aa 25-257)

Vtcn1 Swiss Prot#

Q501W4

Vtcn1 Protein names

V-set domain-containing T-cell activation inhibitor 1

Vtcn1 Gene names

Vtcn1

Organism

Rat

Vtcn1 Entry name

VTCN1_RAT

Vtcn1 Codon optimized cDNA(gene) Clone

Vtcn1 Cat #

RPA0941

Tag

Vtcn1 contains A 6x histidine tag

Vtcn1 Formulation

Liquid

Vtcn1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Vtcn1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Vtcn1 Protein

Vtcn1 Cat #

PA0941

Vtcn1 Source

recombinant

Vtcn1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Vtcn1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Vtcn1 Activity

N/A

Tag

Vtcn1 Contains A 6x histidine tag

Vtcn1 Formulation

Liquid

Vtcn1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Vtcn1 family

Immunoglobulin superfamily, BTN/MOG family

Vtcn1 Subcellular locations

Cell membrane; Lipid-anchor > GPI-anchor.

Vtcn1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation (By similarity).

Vtcn1 Sequence

DDBJ

EMBL

GenBank

Vtcn1 3D structure

ModBase

Vtcn1 interaction

STRING

Vtcn1 Proteomic

PRIDE

Vtcn1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Vtcn1 Organism specific

CTD

MGI

Vtcn1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Vtcn1 Gene expression

Bgee

ArrayExpress

Genevestigator

Vtcn1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY