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Rat Tumor necrosis factor 1-receptor superfamily 1A (aa 22-461)

Tnfr-1 Swiss Prot#

P22934

Tnfr-1 Protein names

Tumor necrosis factor 1-receptor superfamily member 1A (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) (CD antigen CD120a)

Tnfr-1 Gene names

Tnfrsf1a (Tnfr-1) (Tnfr1)

Organism

Rat

Tnfr-1 Entry name

TNR1A_RAT

Tnfr-1 Codon optimized cDNA(gene) Clone

Tnfr-1 Cat #

RPA0939

Tag

Tnfr-1 contains A 6x histidine tag

Tnfr-1 Formulation

Liquid

Tnfr-1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Tnfr-1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Tnfr-1 Protein

Tnfr-1 Cat #

PA0939

Tnfr-1 Source

recombinant

Tnfr-1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Tnfr-1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Tnfr-1 Activity

N/A

Tag

Tnfr-1 Contains A 6x histidine tag

Tnfr-1 Formulation

Liquid

Tnfr-1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Tnfr-1 family

-

Tnfr-1 Subcellular locations

Membrane; Single-pass type I membrane protein.

Tnfr-1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis (By similarity).

Tnfr-1 Sequence

DDBJ

EMBL

GenBank

Tnfr-1 3D structure

ModBase

Tnfr-1 interaction

STRING

Tnfr-1 Proteomic

PRIDE

Tnfr-1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Tnfr-1 Organism specific

CTD

MGI

Tnfr-1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Tnfr-1 Gene expression

Bgee

ArrayExpress

Genevestigator

Tnfr-1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY