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Rat Tumor necrosis factor ligand superfamily 6 (aa 1-278)

Apt1Lg1 Swiss Prot#

P36940

Apt1Lg1 Protein names

Tumor necrosis factor ligand superfamily member 6 (Fas antigen ligand) (Fas ligand) (CD95L protein) (CD antigen CD178) [Cleaved into: Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble form]

Apt1Lg1 Gene names

Faslg (Apt1Lg1) (Fasl) (Tnfsf6)

Organism

Rat

Apt1Lg1 Entry name

TNFL6_RAT

Apt1Lg1 Codon optimized cDNA(gene) Clone

Apt1Lg1 Cat #

RPA0937

Tag

Apt1Lg1 contains A 6x histidine tag

Apt1Lg1 Formulation

Liquid

Apt1Lg1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Apt1Lg1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Apt1Lg1 Protein

Apt1Lg1 Cat #

PA0937

Apt1Lg1 Source

recombinant

Apt1Lg1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Apt1Lg1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Apt1Lg1 Activity

N/A

Tag

Apt1Lg1 Contains A 6x histidine tag

Apt1Lg1 Formulation

Liquid

Apt1Lg1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Apt1Lg1 family

Tumor necrosis factor family

Apt1Lg1 Subcellular locations

Cell membrane; Single-pass type II membrane protein. Secreted.

Apt1Lg1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects (By similarity).

Apt1Lg1 Sequence

DDBJ

EMBL

GenBank

Apt1Lg1 3D structure

ModBase

Apt1Lg1 interaction

STRING

Apt1Lg1 Proteomic

PRIDE

Apt1Lg1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Apt1Lg1 Organism specific

CTD

MGI

Apt1Lg1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Apt1Lg1 Gene expression

Bgee

ArrayExpress

Genevestigator

Apt1Lg1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY