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Rat Serglycin (aa 27-179)

Pgsg Swiss Prot#

P04917

Pgsg Protein names

Serglycin (Secretory granule proteoglycan core protein) (Chondroitin sulfate proteoglycan core protein) (Proteoglycan 10K core protein) (PG19 core protein) (Cytolytic granule proteoglycan core protein)

Pgsg Gene names

Srgn (Pgsg) (Prg) (Prg1)

Organism

Rat

Pgsg Entry name

SRGN_RAT

Pgsg Codon optimized cDNA(gene) Clone

Pgsg Cat #

RPA0917

Tag

Pgsg contains A 6x histidine tag

Pgsg Formulation

Liquid

Pgsg Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Pgsg Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Pgsg Protein

Pgsg Cat #

PA0917

Pgsg Source

recombinant

Pgsg Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Pgsg Purity

>90%, as determined by SDS-PAGE under reducing conditions

Pgsg Activity

N/A

Tag

Pgsg Contains A 6x histidine tag

Pgsg Formulation

Liquid

Pgsg Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Pgsg family

Serglycin family

Pgsg Subcellular locations

Cytoplasmic granule. Secreted > extracellular space. Golgi apparatus.

Pgsg FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Plays a role in formation of mast cell secretory granules and mediates storage of various compounds in secretory vesicles. Required for storage of some proteases in both connective tissue and mucosal mast cells and for storage of granzyme B in T lymphocytes. Plays a role in localizing neutrophil elastase in azurophil granules of neutrophils. Mediates processing of MMP2. Plays a role in cytotoxic cell granule-mediated apoptosis by forming a complex with granzyme B which is delivered to cells by perforin to induce apoptosis. Regulates the secretion of TNF-alpha and may also regulate protease secretion. Inhibits bone mineralization (By similarity).

Pgsg Sequence

DDBJ

EMBL

GenBank

Pgsg 3D structure

ModBase

Pgsg interaction

STRING

Pgsg Proteomic

PRIDE

Pgsg Genome annotation

Ensembl

GeneID

KEGG

UCSC

Pgsg Organism specific

CTD

MGI

Pgsg Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Pgsg Gene expression

Bgee

ArrayExpress

Genevestigator

Pgsg Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY