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Mouse Tumor necrosis factor ligand superfamily 11 (aa 1-316)

Opgl Swiss Prot#

O35235

Opgl Protein names

Tumor necrosis factor ligand superfamily member 11 (1-receptor activator of nuclear factor kappa B ligand) (RANKL) (TNF-related activation-induced cytokine) (TRANCE) (Osteoprotegerin ligand) (OPGL) (Osteoclast differentiation factor) (ODF) (CD antigen CD254) [Cleaved into: Tumor necrosis factor ligand superfamily member 11, membrane form; Tumor necrosis factor ligand superfamily member 11, soluble form]

Opgl Gene names

Tnfsf11 (Opgl) (Rankl) (Trance)

Organism

Mouse

Opgl Entry name

TNF11_MOUSE

Opgl Codon optimized cDNA(gene) Clone

Opgl Cat #

RPA0712

Tag

Opgl contains A 6x histidine tag

Opgl Formulation

Liquid

Opgl Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Opgl Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Opgl Protein

Opgl Cat #

PA0712

Opgl Source

recombinant

Opgl Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Opgl Purity

>90%, as determined by SDS-PAGE under reducing conditions

Opgl Activity

N/A

Tag

Opgl Contains A 6x histidine tag

Opgl Formulation

Liquid

Opgl Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Opgl family

Tumor necrosis factor family

Opgl Subcellular locations

Cell membrane; Single-pass type II membrane protein. Cytoplasm. Secreted.

Opgl FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. May also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy.

Opgl Sequence

DDBJ

EMBL

GenBank

Opgl 3D structure

ModBase

Opgl interaction

STRING

Opgl Proteomic

PRIDE

Opgl Genome annotation

Ensembl

GeneID

KEGG

UCSC

Opgl Organism specific

CTD

MGI

Opgl Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Opgl Gene expression

Bgee

ArrayExpress

Genevestigator

Opgl Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY