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Mouse Transcription elongation factor B polypeptide 2 (aa 1-118)
Tceb2 Swiss Prot#
P62869
Tceb2 Protein names
Transcription elongation factor B polypeptide 2 (RNA polymerase II transcription factor SIII subunit B) (SIII p18) (Elongin B) (EloB) (Elongin 18 kDa subunit)
Tceb2 Gene names
Tceb2
Organism
Mouse
Tceb2 Entry name
ELOB_MOUSE
Tceb2 Codon optimized cDNA(gene) Clone
Tceb2 Cat #
RPA0706
Tag
Tceb2 contains A 6x histidine tag
Tceb2 Formulation
Liquid
Tceb2 Storage
Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
Tceb2 Applications
Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant Tceb2 Protein
Tceb2 Cat #
PA0706
Tceb2 Source
recombinant
Tceb2 Applications
Western Blot, SDS-Page or may be used for other applications determined by user
Tceb2 Purity
>90%, as determined by SDS-PAGE under reducing conditions
Tceb2 Activity
N/A
Tag
Tceb2 Contains A 6x histidine tag
Tceb2 Formulation
Liquid
Tceb2 Storage
;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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Tceb2 family
-
Tceb2 Subcellular locations
Nucleus.
Tceb2 FUNCTION According to UniProtKB Swiss Prot
FUNCTION: SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex).; FUNCTION: The elongin BC complex seems to be involved as an adapter protein in the proteasomal degradation of target proteins via different E3 ubiquitin ligase complexes, including the von Hippel-Lindau ubiquitination complex CBC(VHL). By binding to BC-box motifs it seems to link target recruitment subunits, like VHL and members of the SOCS box family, to Cullin/RBX1 modules that activate E2 ubiquitination enzymes.
Tceb2 Sequence
DDBJ EMBL GenBank
Tceb2 3D structure
ModBase
Tceb2 interaction
STRING
Tceb2 Proteomic
PRIDE
Tceb2 Genome annotation
Ensembl GeneID KEGG UCSC
Tceb2 Organism specific
CTD MGI
Tceb2 Phylogenomics
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
Tceb2 Gene expression
Bgee ArrayExpress Genevestigator
Tceb2 Family and domain
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY