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Mouse TIR domain-containing adapter molecule 2 (aa 1-232)

Tirp Swiss Prot#

Q8BJQ4

Tirp Protein names

TIR domain-containing adapter molecule 2 (TICAM-2) (TRIF-related adapter molecule) (Toll/interleukin-1 1-receptor domain-containing protein)

Tirp Gene names

Ticam2 (Tirp) (Tram)

Organism

Mouse

Tirp Entry name

TCAM2_MOUSE

Tirp Codon optimized cDNA(gene) Clone

Tirp Cat #

RPA0700

Tag

Tirp contains A 6x histidine tag

Tirp Formulation

Liquid

Tirp Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Tirp Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Tirp Protein

Tirp Cat #

PA0700

Tirp Source

recombinant

Tirp Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Tirp Purity

>90%, as determined by SDS-PAGE under reducing conditions

Tirp Activity

N/A

Tag

Tirp Contains A 6x histidine tag

Tirp Formulation

Liquid

Tirp Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Tirp family

-

Tirp Subcellular locations

Cytoplasm. Golgi apparatus. Cell membrane.

Tirp FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Functions in LPS-TLR4 signaling to regulate the MYD88-independent pathway during the innate immune response to LPS. Also involved in IL1-triggered NF-kappa-B activation, functioning upstream of IRAK1, IRAK2, TRAF6, and IKBKB. Physically bridges TLR4 and TICAM1 and functionally transmits LPS-TRL4 signal to TICAM1 (By similarity).

Tirp Sequence

DDBJ

EMBL

GenBank

Tirp 3D structure

ModBase

Tirp interaction

STRING

Tirp Proteomic

PRIDE

Tirp Genome annotation

Ensembl

GeneID

KEGG

UCSC

Tirp Organism specific

CTD

MGI

Tirp Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Tirp Gene expression

Bgee

ArrayExpress

Genevestigator

Tirp Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY