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Mouse Serine protease inhibitor A3G (aa 1-440)

Spi2A Swiss Prot#

Q5I2A0

Spi2A Protein names

Serine protease inhibitor A3G (Serpin A3G) (Serine protease inhibitor 2A) (Serpin 2A)

Spi2A Gene names

Serpina3g (Spi2A)

Organism

Mouse

Spi2A Entry name

SPA3G_MOUSE

Spi2A Codon optimized cDNA(gene) Clone

Spi2A Cat #

RPA0673

Tag

Spi2A contains A 6x histidine tag

Spi2A Formulation

Liquid

Spi2A Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Spi2A Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Spi2A Protein

Spi2A Cat #

PA0673

Spi2A Source

recombinant

Spi2A Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Spi2A Purity

>90%, as determined by SDS-PAGE under reducing conditions

Spi2A Activity

N/A

Tag

Spi2A Contains A 6x histidine tag

Spi2A Formulation

Liquid

Spi2A Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Spi2A family

Serpin family

Spi2A Subcellular locations

Cytoplasm. Nucleus.

Spi2A FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Serine and cysteine protease inhibitor. Can inhibit lysosomal papain-like proteases including the cathepsins B, G, H, K, L and V. Ineffective against elastase, granzyme A, granzyme B, or caspases 3, 8 or 9. Inhibition of cytoplasmic cathepsin B following release from the lysosome may protect cells from apoptosis. This may facilitate the survival of progenitor T-cells and the subsequent development of long term memory CD8 T-cells.

Spi2A Sequence

DDBJ

EMBL

GenBank

Spi2A 3D structure

ModBase

Spi2A interaction

STRING

Spi2A Proteomic

PRIDE

Spi2A Genome annotation

Ensembl

GeneID

KEGG

UCSC

Spi2A Organism specific

CTD

MGI

Spi2A Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Spi2A Gene expression

Bgee

ArrayExpress

Genevestigator

Spi2A Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY