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Mouse Serglycin (aa 26-152)

Prg Swiss Prot#

P13609

Prg Protein names

Serglycin (Secretory granule proteoglycan core protein) (Mastocytoma proteoglycan core protein) (gp600)

Prg Gene names

Srgn (Prg) (Prg1)

Organism

Mouse

Prg Entry name

SRGN_MOUSE

Prg Codon optimized cDNA(gene) Clone

Prg Cat #

RPA0669

Tag

Prg contains A 6x histidine tag

Prg Formulation

Liquid

Prg Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Prg Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Prg Protein

Prg Cat #

PA0669

Prg Source

recombinant

Prg Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Prg Purity

>90%, as determined by SDS-PAGE under reducing conditions

Prg Activity

N/A

Tag

Prg Contains A 6x histidine tag

Prg Formulation

Liquid

Prg Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Prg family

Serglycin family

Prg Subcellular locations

Cytoplasmic granule. Secreted > extracellular space. Golgi apparatus.

Prg FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Plays a role in formation of mast cell secretory granules and mediates storage of various compounds in secretory vesicles. Required for storage of some proteases in both connective tissue and mucosal mast cells and for storage of granzyme B in T lymphocytes. Plays a role in localizing neutrophil elastase in azurophil granules of neutrophils. Mediates processing of MMP2. Plays a role in cytotoxic cell granule-mediated apoptosis by forming a complex with granzyme B which is delivered to cells by perforin to induce apoptosis. Regulates the secretion of TNF-alpha and may also regulate protease secretion. Inhibits bone mineralization.

Prg Sequence

DDBJ

EMBL

GenBank

Prg 3D structure

ModBase

Prg interaction

STRING

Prg Proteomic

PRIDE

Prg Genome annotation

Ensembl

GeneID

KEGG

UCSC

Prg Organism specific

CTD

MGI

Prg Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Prg Gene expression

Bgee

ArrayExpress

Genevestigator

Prg Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY