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Mouse Prostaglandin-H2 D-isomerase (aa 25-189)

Ptgds Swiss Prot#

O09114

Ptgds Protein names

Prostaglandin-H2 D-isomerase (EC 5.3.99.2) (Lipocalin-type prostaglandin-D synthase) (Glutathione-independent PGD synthetase) (Prostaglandin-D2 synthase) (PGD2 synthase) (PGDS2) (PGDS)

Ptgds Gene names

Ptgds

Organism

Mouse

Ptgds Entry name

PTGDS_MOUSE

Ptgds Codon optimized cDNA(gene) Clone

Ptgds Cat #

RPA0660

Tag

Ptgds contains A 6x histidine tag

Ptgds Formulation

Liquid

Ptgds Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Ptgds Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Ptgds Protein

Ptgds Cat #

PA0660

Ptgds Source

recombinant

Ptgds Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Ptgds Purity

>90%, as determined by SDS-PAGE under reducing conditions

Ptgds Activity

N/A

Tag

Ptgds Contains A 6x histidine tag

Ptgds Formulation

Liquid

Ptgds Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Ptgds family

Calycin superfamily, Lipocalin family

Ptgds Subcellular locations

Rough endoplasmic reticulum. Nucleus membrane. Golgi apparatus. Cytoplasm > perinuclear region. Secreted.

Ptgds FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. Involved in a variety of CNS functions, such as sedation, NREM sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes. Binds small non-substrate lipophilic molecules, including biliverdin, bilirubin, retinal, retinoic acid and thyroid hormone, and may act as a scavenger for harmful hydrophopic molecules and as a secretory retinoid and thyroid hormone transporter. Possibly involved in development and maintenance of the blood-brain, blood-retina, blood-aqueous humor and blood-testis barrier. It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system.

Ptgds Sequence

DDBJ

EMBL

GenBank

Ptgds 3D structure

ModBase

Ptgds interaction

STRING

Ptgds Proteomic

PRIDE

Ptgds Genome annotation

Ensembl

GeneID

KEGG

UCSC

Ptgds Organism specific

CTD

MGI

Ptgds Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Ptgds Gene expression

Bgee

ArrayExpress

Genevestigator

Ptgds Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY