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Mouse Interleukin-27 subunit beta (aa 19-228)

Il17b Swiss Prot#

O35228

Il17b Protein names

Interleukin-27 subunit beta (IL-27 subunit beta) (IL-27B) (Epstein-Barr virus-induced gene 3 protein homolog)

Il17b Gene names

Ebi3 (Il17b)

Organism

Mouse

Il17b Entry name

IL27B_MOUSE

Il17b Codon optimized cDNA(gene) Clone

Il17b Cat #

RPA0572

Tag

Il17b contains A 6x histidine tag

Il17b Formulation

Liquid

Il17b Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Il17b Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Il17b Protein

Il17b Cat #

PA0572

Il17b Source

recombinant

Il17b Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Il17b Purity

>90%, as determined by SDS-PAGE under reducing conditions

Il17b Activity

N/A

Tag

Il17b Contains A 6x histidine tag

Il17b Formulation

Liquid

Il17b Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Il17b family

Type I cytokine receptor family, Type 3 subfamily

Il17b Subcellular locations

Secreted.

Il17b FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Cytokine with pro- and anti-inflammatory properties, that can regulate T helper cell development, suppress T-cell proliferation, stimulate cytotoxic T cell activity, induce isotype switching in B-cells, and that has diverse effects on innate immune cells. Among its target cells are CD4 T helper cells which can differentiate in type 1 effector cells (TH1), type 2 effector cells (TH2) and IL17 producing helper T-cells (TH17). It drives rapid clonal expansion of naive but not memory CD4 T-cells. It also strongly synergizes with IL-12 to trigger interferon-gamma/IFN-gamma production of naive CD4 T-cells, binds to the cytokine receptor WSX-1/TCCR. Another important role of IL27 is its antitumor activity as well as its antiangiogenic activity with activation of production of antiangiogenic chemokines.

Il17b Sequence

DDBJ

EMBL

GenBank

Il17b 3D structure

ModBase

Il17b interaction

STRING

Il17b Proteomic

PRIDE

Il17b Genome annotation

Ensembl

GeneID

KEGG

UCSC

Il17b Organism specific

CTD

MGI

Il17b Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Il17b Gene expression

Bgee

ArrayExpress

Genevestigator

Il17b Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY