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Mouse H-2 class II histocompatibility antigen gamma (aa 1-279)

Ii Swiss Prot#

P04441

Ii Protein names

H-2 class II histocompatibility antigen gamma chain (MHC class II-associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (CD antigen CD74)

Ii Gene names

Cd74 (Ii)

Organism

Mouse

Ii Entry name

HG2A_MOUSE

Ii Codon optimized cDNA(gene) Clone

Ii Cat #

RPA0487

Tag

Ii contains A 6x histidine tag

Ii Formulation

Liquid

Ii Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Ii Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Ii Protein

Ii Cat #

PA0487

Ii Source

recombinant

Ii Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Ii Purity

>90%, as determined by SDS-PAGE under reducing conditions

Ii Activity

N/A

Tag

Ii Contains A 6x histidine tag

Ii Formulation

Liquid

Ii Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Ii family

-

Ii Subcellular locations

Membrane; Single-pass type II membrane protein.

Ii FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place.

Ii Sequence

DDBJ

EMBL

GenBank

Ii 3D structure

ModBase

Ii interaction

STRING

Ii Proteomic

PRIDE

Ii Genome annotation

Ensembl

GeneID

KEGG

UCSC

Ii Organism specific

CTD

MGI

Ii Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Ii Gene expression

Bgee

ArrayExpress

Genevestigator

Ii Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY