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Mouse Docking protein 2 (aa 1-412)

Frip Swiss Prot#

O70469

Frip Protein names

Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)) (Dok-related protein) (Dok-R) (IL-four 1-receptor-interacting protein) (FRIP)

Frip Gene names

Dok2 (Frip)

Organism

Mouse

Frip Entry name

DOK2_MOUSE

Frip Codon optimized cDNA(gene) Clone

Frip Cat #

RPA0457

Tag

Frip contains A 6x histidine tag

Frip Formulation

Liquid

Frip Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Frip Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Frip Protein

Frip Cat #

PA0457

Frip Source

recombinant

Frip Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Frip Purity

>90%, as determined by SDS-PAGE under reducing conditions

Frip Activity

N/A

Tag

Frip Contains A 6x histidine tag

Frip Formulation

Liquid

Frip Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Frip family

DOK family, Type A subfamily

Frip Subcellular locations

-

Frip FUNCTION According to UniProtKB Swiss Prot

FUNCTION: DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK2 may modulate the cellular proliferation induced by IL-4, as well as IL-2 and IL-3. May be involved in modulating Bcr-Abl signaling. Attenuates EGF-stimulated MAP kinase activation.

Frip Sequence

DDBJ

EMBL

GenBank

Frip 3D structure

ModBase

Frip interaction

STRING

Frip Proteomic

PRIDE

Frip Genome annotation

Ensembl

GeneID

KEGG

UCSC

Frip Organism specific

CTD

MGI

Frip Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Frip Gene expression

Bgee

ArrayExpress

Genevestigator

Frip Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY