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Human Tumor necrosis factor ligand superfamily 10 (a.a.27–181)
APO2L Swiss Prot#
P50591
APO2L Protein names
Tumor necrosis factor ligand superfamily member 10 (TNF-related apoptosis-inducing ligand) (Protein TRAIL) (Apo-2 ligand) (Apo-2L) (CD antigen CD253)
APO2L Gene names
TNFSF10 APO2L TRAIL
Organism
Human
APO2L Entry name
TNF10_HUMAN
APO2L Codon optimized cDNA(gene) Clone
APO2L Cat #
RPA0338
Tag
APO2L contains A 6x histidine tag
APO2L Formulation
Liquid
APO2L Storage
Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
APO2L Applications
Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant APO2L Protein
APO2L Cat #
PA0338
APO2L Source
recombinant
APO2L Applications
Western Blot, SDS-Page or may be used for other applications determined by user
APO2L Purity
>90%, as determined by SDS-PAGE under reducing conditions
APO2L Activity
N/A
Tag
APO2L Contains A 6x histidine tag
APO2L Formulation
Liquid
APO2L Storage
;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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APO2L family
Tumor necrosis factor family
APO2L Subcellular locations
Membrane; Single-pass type II membrane protein.
APO2L FUNCTION According to UniProtKB Swiss Prot
FUNCTION: Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis.
APO2L Sequence
DDBJ EMBL GenBank
APO2L 3D structure
ModBase
APO2L interaction
STRING
APO2L Proteomic
PRIDE
APO2L Genome annotation
Ensembl GeneID KEGG UCSC
APO2L Organism specific
CTD MGI
APO2L Phylogenomics
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
APO2L Gene expression
Bgee ArrayExpress Genevestigator
APO2L Family and domain
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY