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| Human Tumor necrosis factor ligand superfamily 10 (a.a.27–181) |
| APO2L Swiss Prot# | | P50591 |
| APO2L Protein names | | Tumor necrosis factor ligand superfamily member 10 (TNF-related apoptosis-inducing ligand) (Protein TRAIL) (Apo-2 ligand) (Apo-2L) (CD antigen CD253) |
| APO2L Gene names | | TNFSF10 APO2L TRAIL |
| Organism | | Human |
| APO2L Entry name | | TNF10_HUMAN |
| APO2L Codon optimized cDNA(gene) Clone |
| APO2L Cat # | | RPA0338 |
| Tag | | APO2L contains A 6x histidine tag |
| APO2L Formulation | | Liquid |
| APO2L Storage | | Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| APO2L Applications | | Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function. |
| Recombinant APO2L Protein |
| APO2L Cat # | | PA0338 |
| APO2L Source | | recombinant |
| APO2L Applications | | Western Blot, SDS-Page or may be used for other applications determined by user |
| APO2L Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| APO2L Activity | | N/A |
| Tag | | APO2L Contains A 6x histidine tag |
| APO2L Formulation | | Liquid |
| APO2L Storage | | ;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant APO2L Products | | For pricing and availability Click Here >>> |
| APO2L family | | Tumor necrosis factor family |
| APO2L Subcellular locations | | Membrane; Single-pass type II membrane protein. |
| APO2L FUNCTION According to UniProtKB Swiss Prot | | FUNCTION: Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis. |
| APO2L Sequence | | DDBJ | EMBL | GenBank |
| APO2L 3D structure | | ModBase |
| APO2L interaction | | STRING |
| APO2L Proteomic | | PRIDE |
| APO2L Genome annotation | | Ensembl | GeneID | KEGG | UCSC |
| APO2L Organism specific | | CTD | MGI |
| APO2L Phylogenomics | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| APO2L Gene expression | | Bgee | ArrayExpress | Genevestigator |
| APO2L Family and domain | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |