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Human Platelet basic protein (a.a.59-128)

CTAP3 Swiss Prot#

P02775

CTAP3 Protein names

Platelet basic protein (PBP) (C-X-C motif chemokine 7) (Small-inducible cytokine B7) (Leukocyte-derived growth factor) (LDGF) (Macrophage-derived growth factor) (MDGF) [Cleaved into: Connective tissue-activating peptide III (CTAP-III) (Low-affinity platelet factor IV) (LA-PF4) TC-2; Connective tissue-activating peptide III(1-81) (CTAP-III(1-81)) Beta-thromboglobulin (Beta-TG) Neutrophil-activating peptide 2(74) (NAP-2(74)) Neutrophil-activating peptide 2(73) (NAP-2(73)) Neutrophil-activating peptide 2 (NAP-2) TC-1; Neutrophil-activating peptide 2(1-66) (NAP-2(1-66)) Neutrophil-activating peptide 2(1-63) (NAP-2(1-63))]

CTAP3 Gene names

PPBP CTAP3 CXCL7 SCYB7 TGB1 THBGB1

Organism

Human

CTAP3 Entry name

CXCL7_HUMAN

CTAP3 Codon optimized cDNA(gene) Clone

CTAP3 Cat #

RPA0285

Tag

CTAP3 contains A 6x histidine tag

CTAP3 Formulation

Liquid

CTAP3 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

CTAP3 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant CTAP3 Protein

CTAP3 Cat #

PA0285

CTAP3 Source

recombinant

CTAP3 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

CTAP3 Purity

>90%, as determined by SDS-PAGE under reducing conditions

CTAP3 Activity

N/A

Tag

CTAP3 Contains A 6x histidine tag

CTAP3 Formulation

Liquid

CTAP3 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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CTAP3 family

Intercrine alpha (chemokine CxC) family

CTAP3 Subcellular locations

Secreted.

CTAP3 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: LA-PF4 stimulates DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by human synovial cells. NAP-2 is a ligand for CXCR1 and CXCR2, and NAP-2, NAP-2(73), NAP-2(74), NAP-2(1-66), and most potent NAP-2(1-63) are chemoattractants and activators for neutrophils. TC-1 and TC-2 are antibacterial proteins, in vitro released from activated platelet alpha-granules. CTAP-III(1-81) is more potent than CTAP-III desensitize chemokine-induced neutrophil activation.

CTAP3 Sequence

DDBJ

EMBL

GenBank

CTAP3 3D structure

ModBase

CTAP3 interaction

STRING

CTAP3 Proteomic

PRIDE

CTAP3 Genome annotation

Ensembl

GeneID

KEGG

UCSC

CTAP3 Organism specific

CTD

MGI

CTAP3 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

CTAP3 Gene expression

Bgee

ArrayExpress

Genevestigator

CTAP3 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY