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Human Insulin-like growth factor II (a.a.25-91)

PP1446 Swiss Prot#

P01344

PP1446 Protein names

Insulin-like growth factor II (IGF-II) (Somatomedin-A) [Cleaved into: Insulin-like growth factor II Ala-25 Del; Preptin]

PP1446 Gene names

IGF2 PP1446

Organism

Human

PP1446 Entry name

IGF2_HUMAN

PP1446 Codon optimized cDNA(gene) Clone

PP1446 Cat #

RPA0278

Tag

PP1446 contains A 6x histidine tag

PP1446 Formulation

Liquid

PP1446 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

PP1446 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant PP1446 Protein

PP1446 Cat #

PA0278

PP1446 Source

recombinant

PP1446 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

PP1446 Purity

>90%, as determined by SDS-PAGE under reducing conditions

PP1446 Activity

N/A

Tag

PP1446 Contains A 6x histidine tag

PP1446 Formulation

Liquid

PP1446 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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PP1446 family

Insulin family

PP1446 Subcellular locations

Secreted.

PP1446 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: The insulin-like growth factors possess growth-promoting activity. In vitro, they are potent mitogens for cultured cells. IGF-II is influenced by placental lactogen and may play a role in fetal development.; FUNCTION: Preptin undergoes glucose-mediated co-secretion with insulin, and acts as physiological amplifier of glucose-mediated insulin secretion. Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3.

PP1446 Sequence

DDBJ

EMBL

GenBank

PP1446 3D structure

ModBase

PP1446 interaction

STRING

PP1446 Proteomic

PRIDE

PP1446 Genome annotation

Ensembl

GeneID

KEGG

UCSC

PP1446 Organism specific

CTD

MGI

PP1446 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

PP1446 Gene expression

Bgee

ArrayExpress

Genevestigator

PP1446 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY