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Human Toll-like receptor 2 (a.a.1-171)

TIL4 Swiss Prot#

O60603

TIL4 Protein names

Toll-like receptor 2 (Toll/interleukin-1 receptor-like protein 4) (CD antigen CD282)

TIL4 Gene names

TLR2 TIL4

Organism

Human

TIL4 Entry name

TLR2_HUMAN

TIL4 Codon optimized cDNA(gene) Clone

TIL4 Cat #

RPA0269

Tag

TIL4 contains A 6x histidine tag

TIL4 Formulation

Liquid

TIL4 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

TIL4 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant TIL4 Protein

TIL4 Cat #

PA0269

TIL4 Source

recombinant

TIL4 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

TIL4 Purity

>90%, as determined by SDS-PAGE under reducing conditions

TIL4 Activity

N/A

Tag

TIL4 Contains A 6x histidine tag

TIL4 Formulation

Liquid

TIL4 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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TIL4 family

Toll-like receptor family

TIL4 Subcellular locations

Membrane; Single-pass type I membrane protein.

TIL4 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR6.

TIL4 Sequence

DDBJ

EMBL

GenBank

TIL4 3D structure

ModBase

TIL4 interaction

STRING

TIL4 Proteomic

PRIDE

TIL4 Genome annotation

Ensembl

GeneID

KEGG

UCSC

TIL4 Organism specific

CTD

MGI

TIL4 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

TIL4 Gene expression

Bgee

ArrayExpress

Genevestigator

TIL4 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY