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Human C-C motif chemokine 22 (a.a.25-93)

MDC Swiss Prot#

O00626

MDC Protein names

C-C motif chemokine 22 (Small-inducible cytokine A22) (Macrophage-derived chemokine) (MDC(1-69)) (Stimulated T-cell chemotactic protein 1) (CC chemokine STCP-1) [Cleaved into: MDC(3-69) MDC(5-69) MDC(7-69)]

MDC Gene names

CCL22 MDC SCYA22 A-152E5.1

Organism

Human

MDC Entry name

CCL22_HUMAN

MDC Codon optimized cDNA(gene) Clone

MDC Cat #

RPA0256

Tag

MDC contains A 6x histidine tag

MDC Formulation

Liquid

MDC Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

MDC Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant MDC Protein

MDC Cat #

PA0256

MDC Source

recombinant

MDC Applications

Western Blot, SDS-Page or may be used for other applications determined by user

MDC Purity

>90%, as determined by SDS-PAGE under reducing conditions

MDC Activity

N/A

Tag

MDC Contains A 6x histidine tag

MDC Formulation

Liquid

MDC Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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MDC family

Intercrine beta (chemokine CC) family

MDC Subcellular locations

Secreted.

MDC FUNCTION According to UniProtKB Swiss Prot

FUNCTION: May play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. Chemotactic for monocytes, dendritic cells and natural killer cells. Mild chemoattractant for primary activated T-lymphocytes and a potent chemoattractant for chronically activated T-lymphocytes but has no chemoattractant activity for neutrophils, eosinophils, and resting T-lymphocytes. Binds to CCR4. Processed forms MDC(3-69), MDC(5-69) and MDC(7-69) seem not be active.

MDC Sequence

DDBJ

EMBL

GenBank

MDC 3D structure

ModBase

MDC interaction

STRING

MDC Proteomic

PRIDE

MDC Genome annotation

Ensembl

GeneID

KEGG

UCSC

MDC Organism specific

CTD

MGI

MDC Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

MDC Gene expression

Bgee

ArrayExpress

Genevestigator

MDC Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY