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Human Ubiquitin carboxyl-terminal hydrolase 17-like 2 (aa 1-530)

DUB3 Swiss Prot#

Q6R6M4

DUB3 Protein names

Ubiquitin carboxyl-terminal hydrolase 17-like protein 2 (EC 3.1.2.15) (Ubiquitin thioesterase 17-like protein 2) (Ubiquitin-specific-processing protease 17-like protein 2) (Deubiquitinating enzyme 17-like protein 2) (Deubiquitinating protein 3) (DUB-3)

DUB3 Gene names

USP17L2 (DUB3)

Organism

Human

DUB3 Entry name

U17L2_HUMAN

DUB3 Codon optimized cDNA(gene) Clone

DUB3 Cat #

RPA0249

Tag

DUB3 contains A 6x histidine tag

DUB3 Formulation

Liquid

DUB3 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

DUB3 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant DUB3 Protein

DUB3 Cat #

PA0249

DUB3 Source

recombinant

DUB3 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

DUB3 Purity

>90%, as determined by SDS-PAGE under reducing conditions

DUB3 Activity

N/A

Tag

DUB3 Contains A 6x histidine tag

DUB3 Formulation

Liquid

DUB3 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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DUB3 family

Peptidase C19 family, USP17 subfamily

DUB3 Subcellular locations

Nucleus.

DUB3 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Deubiquitinating enzyme that specifically removes conjugated ubiquitin from CDC25A, thereby playing a key role in cell cycle regulation. Deubiquitination of CDC25A prevents its degradation by the proteasome during the G1/S and G2/M phases of the cell cycle and is required for cell-cycle progression. Has transforming capabilities on cell lines. May also function in cell apoptosis.

DUB3 Sequence

DDBJ

EMBL

GenBank

DUB3 3D structure

ModBase

DUB3 interaction

STRING

DUB3 Proteomic

PRIDE

DUB3 Genome annotation

Ensembl

GeneID

KEGG

UCSC

DUB3 Organism specific

CTD

MGI

DUB3 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

DUB3 Gene expression

Bgee

ArrayExpress

Genevestigator

DUB3 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY