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| Human Tumor necrosis factor ligand superfamily 12 (aa 1-249) |
| APO3L Swiss Prot# | | O43508 |
| APO3L Protein names | | Tumor necrosis factor ligand superfamily member 12 (TNF-related weak inducer of apoptosis) (TWEAK) (APO3 ligand) [Cleaved into: Tumor necrosis factor ligand superfamily member 12, membrane form; Tumor necrosis factor ligand superfamily member 12, secreted form] |
| APO3L Gene names | | TNFSF12 (APO3L) (DR3LG) (UNQ181/PRO207) |
| Organism | | Human |
| APO3L Entry name | | TNF12_HUMAN |
| APO3L Codon optimized cDNA(gene) Clone |
| APO3L Cat # | | RPA0242 |
| Tag | | APO3L contains A 6x histidine tag |
| APO3L Formulation | | Liquid |
| APO3L Storage | | Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| APO3L Applications | | Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function. |
| Recombinant APO3L Protein |
| APO3L Cat # | | PA0242 |
| APO3L Source | | recombinant |
| APO3L Applications | | Western Blot, SDS-Page or may be used for other applications determined by user |
| APO3L Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| APO3L Activity | | N/A |
| Tag | | APO3L Contains A 6x histidine tag |
| APO3L Formulation | | Liquid |
| APO3L Storage | | ;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant APO3L Products | | For pricing and availability Click Here >>> |
| APO3L family | | Tumor necrosis factor family |
| APO3L Subcellular locations | | Cell membrane; Single-pass type II membrane protein. Secreted. |
| APO3L FUNCTION According to UniProtKB Swiss Prot | | FUNCTION: Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. |
| APO3L Sequence | | DDBJ | EMBL | GenBank |
| APO3L 3D structure | | ModBase |
| APO3L interaction | | STRING |
| APO3L Proteomic | | PRIDE |
| APO3L Genome annotation | | Ensembl | GeneID | KEGG | UCSC |
| APO3L Organism specific | | CTD | MGI |
| APO3L Phylogenomics | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| APO3L Gene expression | | Bgee | ArrayExpress | Genevestigator |
| APO3L Family and domain | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |