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Human TNF 1-receptor-associated factor 2 (aa 1-501)

TRAP3 Swiss Prot#

Q12933

TRAP3 Protein names

TNF 1-receptor-associated factor 2 (Tumor necrosis factor type 2 1-receptor-associated protein 3)

TRAP3 Gene names

TRAF2 (TRAP3)

Organism

Human

TRAP3 Entry name

TRAF2_HUMAN

TRAP3 Codon optimized cDNA(gene) Clone

TRAP3 Cat #

RPA0232

Tag

TRAP3 contains A 6x histidine tag

TRAP3 Formulation

Liquid

TRAP3 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

TRAP3 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant TRAP3 Protein

TRAP3 Cat #

PA0232

TRAP3 Source

recombinant

TRAP3 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

TRAP3 Purity

>90%, as determined by SDS-PAGE under reducing conditions

TRAP3 Activity

N/A

Tag

TRAP3 Contains A 6x histidine tag

TRAP3 Formulation

Liquid

TRAP3 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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TRAP3 family

TNF receptor-associated factor family, A subfamily

TRAP3 Subcellular locations

Cytoplasm.

TRAP3 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Regulates activation of NF-kappa-B and JNK and plays a central role in the regulation of cell survival and apoptosis. Required for normal antibody isotype switching from IgM to IgG. Has E3 ubiquitin-protein ligase activity and promotes 'Lys-63'-linked ubiquitination of target proteins, such as BIRC3, RIPK1 and TICAM1. Is an essential constituent of several E3 ubiquitin-protein ligase complexes, where it promotes the ubiquitination of target proteins by bringing them into contact with other E3 ubiquitin ligases. Regulates BIRC2 and BIRC3 protein levels by inhibiting their autoubiquitination and subsequent degradation; this does not depend on the TRAF2 RING-type zinc finger domain.

TRAP3 Sequence

DDBJ

EMBL

GenBank

TRAP3 3D structure

ModBase

TRAP3 interaction

STRING

TRAP3 Proteomic

PRIDE

TRAP3 Genome annotation

Ensembl

GeneID

KEGG

UCSC

TRAP3 Organism specific

CTD

MGI

TRAP3 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

TRAP3 Gene expression

Bgee

ArrayExpress

Genevestigator

TRAP3 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY