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Human Signal transducing adapter molecule 1 (aa 1-540)

STAM1 Swiss Prot#

Q92783

STAM1 Protein names

Signal transducing adapter molecule 1 (STAM-1)

STAM1 Gene names

STAM (STAM1)

Organism

Human

STAM1 Entry name

STAM1_HUMAN

STAM1 Codon optimized cDNA(gene) Clone

STAM1 Cat #

RPA0215

Tag

STAM1 contains A 6x histidine tag

STAM1 Formulation

Liquid

STAM1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

STAM1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant STAM1 Protein

STAM1 Cat #

PA0215

STAM1 Source

recombinant

STAM1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

STAM1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

STAM1 Activity

N/A

Tag

STAM1 Contains A 6x histidine tag

STAM1 Formulation

Liquid

STAM1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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STAM1 family

STAM family

STAM1 Subcellular locations

Cytoplasm. Early endosome membrane; Peripheral membrane protein; Cytoplasmic side.

STAM1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes.

STAM1 Sequence

DDBJ

EMBL

GenBank

STAM1 3D structure

ModBase

STAM1 interaction

STRING

STAM1 Proteomic

PRIDE

STAM1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

STAM1 Organism specific

CTD

MGI

STAM1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

STAM1 Gene expression

Bgee

ArrayExpress

Genevestigator

STAM1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY