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Human Programmed cell death 1 ligand 2 (aa 20-273)

B7DC Swiss Prot#

Q9BQ51

B7DC Protein names

Programmed cell death 1 ligand 2 (Programmed death ligand 2) (PD-L2) (PD-1-ligand 2) (PDCD1 ligand 2) (Butyrophilin B7-DC) (B7-DC) (CD antigen CD273)

B7DC Gene names

PDCD1LG2 (B7DC) (CD273) (PDCD1L2) (PDL2)

Organism

Human

B7DC Entry name

PD1L2_HUMAN

B7DC Codon optimized cDNA(gene) Clone

B7DC Cat #

RPA0202

Tag

B7DC contains A 6x histidine tag

B7DC Formulation

Liquid

B7DC Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

B7DC Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant B7DC Protein

B7DC Cat #

PA0202

B7DC Source

recombinant

B7DC Applications

Western Blot, SDS-Page or may be used for other applications determined by user

B7DC Purity

>90%, as determined by SDS-PAGE under reducing conditions

B7DC Activity

N/A

Tag

B7DC Contains A 6x histidine tag

B7DC Formulation

Liquid

B7DC Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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B7DC family

Immunoglobulin superfamily, BTN/MOG family

B7DC Subcellular locations

Secreted. Endomembrane system; Single-pass type I membrane protein. Cell membrane; Single-pass type I membrane protein.

B7DC FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity).

B7DC Sequence

DDBJ

EMBL

GenBank

B7DC 3D structure

ModBase

B7DC interaction

STRING

B7DC Proteomic

PRIDE

B7DC Genome annotation

Ensembl

GeneID

KEGG

UCSC

B7DC Organism specific

CTD

MGI

B7DC Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

B7DC Gene expression

Bgee

ArrayExpress

Genevestigator

B7DC Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY