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Human Nicotinamide phosphoribosyltransferase (aa 1-491)

PBEF Swiss Prot#

P43490

PBEF Protein names

Nicotinamide phosphoribosyltransferase (NAmPRTase) (Nampt) (EC 2.4.2.12) (Pre-B-cell colony-enhancing factor 1) (Pre-B cell-enhancing factor) (Visfatin)

PBEF Gene names

NAMPT (PBEF) (PBEF1)

Organism

Human

PBEF Entry name

NAMPT_HUMAN

PBEF Codon optimized cDNA(gene) Clone

PBEF Cat #

RPA0193

Tag

PBEF contains A 6x histidine tag

PBEF Formulation

Liquid

PBEF Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

PBEF Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant PBEF Protein

PBEF Cat #

PA0193

PBEF Source

recombinant

PBEF Applications

Western Blot, SDS-Page or may be used for other applications determined by user

PBEF Purity

>90%, as determined by SDS-PAGE under reducing conditions

PBEF Activity

N/A

Tag

PBEF Contains A 6x histidine tag

PBEF Formulation

Liquid

PBEF Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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PBEF family

NAPRTase family

PBEF Subcellular locations

Cytoplasm.

PBEF FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway (By similarity).

PBEF Sequence

DDBJ

EMBL

GenBank

PBEF 3D structure

ModBase

PBEF interaction

STRING

PBEF Proteomic

PRIDE

PBEF Genome annotation

Ensembl

GeneID

KEGG

UCSC

PBEF Organism specific

CTD

MGI

PBEF Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

PBEF Gene expression

Bgee

ArrayExpress

Genevestigator

PBEF Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY