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Human NFAT activation molecule 1 (aa 43-270)

CNAIP Swiss Prot#

Q8NET5

CNAIP Protein names

NFAT activation molecule 1 (Calcineurin/NFAT-activating ITAM-containing protein) (NFAT-activating protein with ITAM motif 1)

CNAIP Gene names

NFAM1 (CNAIP)

Organism

Human

CNAIP Entry name

NFAM1_HUMAN

CNAIP Codon optimized cDNA(gene) Clone

CNAIP Cat #

RPA0192

Tag

CNAIP contains A 6x histidine tag

CNAIP Formulation

Liquid

CNAIP Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

CNAIP Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant CNAIP Protein

CNAIP Cat #

PA0192

CNAIP Source

recombinant

CNAIP Applications

Western Blot, SDS-Page or may be used for other applications determined by user

CNAIP Purity

>90%, as determined by SDS-PAGE under reducing conditions

CNAIP Activity

N/A

Tag

CNAIP Contains A 6x histidine tag

CNAIP Formulation

Liquid

CNAIP Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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CNAIP family

-

CNAIP Subcellular locations

Cell membrane; Single-pass type I membrane protein.

CNAIP FUNCTION According to UniProtKB Swiss Prot

FUNCTION: May function in immune system as a receptor which activates via the calcineurin/NFAT-signaling pathway the downstream cytokine gene promoters. Activates the transcription of IL-13 and TNF-alpha promoters. May be involved in the regulation of B-cell, but not T-cell, development. Overexpression activates downstream effectors without ligand binding or antibody cross-linking.

CNAIP Sequence

DDBJ

EMBL

GenBank

CNAIP 3D structure

ModBase

CNAIP interaction

STRING

CNAIP Proteomic

PRIDE

CNAIP Genome annotation

Ensembl

GeneID

KEGG

UCSC

CNAIP Organism specific

CTD

MGI

CNAIP Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

CNAIP Gene expression

Bgee

ArrayExpress

Genevestigator

CNAIP Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY