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Human Leukocyte surface antigen CD47 (aa 19-323)
MER6 Swiss Prot#
Q08722
MER6 Protein names
Leukocyte surface antigen CD47 (Integrin-associated protein) (IAP) (Antigenic surface determinant protein OA3) (Protein MER6) (CD antigen CD47)
MER6 Gene names
CD47 (MER6)
Organism
Human
MER6 Entry name
CD47_HUMAN
MER6 Codon optimized cDNA(gene) Clone
MER6 Cat #
RPA0179
Tag
MER6 contains A 6x histidine tag
MER6 Formulation
Liquid
MER6 Storage
Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
MER6 Applications
Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant MER6 Protein
MER6 Cat #
PA0179
MER6 Source
recombinant
MER6 Applications
Western Blot, SDS-Page or may be used for other applications determined by user
MER6 Purity
>90%, as determined by SDS-PAGE under reducing conditions
MER6 Activity
N/A
Tag
MER6 Contains A 6x histidine tag
MER6 Formulation
Liquid
MER6 Storage
;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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MER6 family
-
MER6 Subcellular locations
Cell membrane; Multi-pass membrane protein.
MER6 FUNCTION According to UniProtKB Swiss Prot
FUNCTION: Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection.
MER6 Sequence
DDBJ EMBL GenBank
MER6 3D structure
ModBase
MER6 interaction
STRING
MER6 Proteomic
PRIDE
MER6 Genome annotation
Ensembl GeneID KEGG UCSC
MER6 Organism specific
CTD MGI
MER6 Phylogenomics
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
MER6 Gene expression
Bgee ArrayExpress Genevestigator
MER6 Family and domain
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY