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Human Interleukin-21 (aa 23-155 )

IL21 Swiss Prot#

Q9HBE4

IL21 Protein names

Interleukin-21 (IL-21) (Za11)

IL21 Gene names

IL21

Organism

Human

IL21 Entry name

IL21_HUMAN

IL21 Codon optimized cDNA(gene) Clone

IL21 Cat #

RPA0157

Tag

IL21 contains A 6x histidine tag

IL21 Formulation

Liquid

IL21 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

IL21 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant IL21 Protein

IL21 Cat #

PA0157

IL21 Source

recombinant

IL21 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

IL21 Purity

>90%, as determined by SDS-PAGE under reducing conditions

IL21 Activity

N/A

Tag

IL21 Contains A 6x histidine tag

IL21 Formulation

Liquid

IL21 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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IL21 family

IL-15/IL-21 family

IL21 Subcellular locations

Secreted.

IL21 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells (By similarity). May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation.

IL21 Sequence

DDBJ

EMBL

GenBank

IL21 3D structure

ModBase

IL21 interaction

STRING

IL21 Proteomic

PRIDE

IL21 Genome annotation

Ensembl

GeneID

KEGG

UCSC

IL21 Organism specific

CTD

MGI

IL21 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

IL21 Gene expression

Bgee

ArrayExpress

Genevestigator

IL21 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY