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| Human Interferon regulatory factor 9 (aa 1-393) |
| ISGF3G Swiss Prot# | | Q00978 |
| ISGF3G Protein names | | Interferon regulatory factor 9 (IRF-9) (Transcriptional regulator ISGF3 subunit gamma) (IFN-alpha-responsive transcription factor subunit) (Interferon-stimulated gene factor 3 gamma) (ISGF3 p48 subunit) (ISGF-3 gamma) |
| ISGF3G Gene names | | IRF9 (ISGF3G) |
| Organism | | Human |
| ISGF3G Entry name | | IRF9_HUMAN |
| ISGF3G Codon optimized cDNA(gene) Clone |
| ISGF3G Cat # | | RPA0121 |
| Tag | | ISGF3G contains A 6x histidine tag |
| ISGF3G Formulation | | Liquid |
| ISGF3G Storage | | Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| ISGF3G Applications | | Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function. |
| Recombinant ISGF3G Protein |
| ISGF3G Cat # | | PA0121 |
| ISGF3G Source | | recombinant |
| ISGF3G Applications | | Western Blot, SDS-Page or may be used for other applications determined by user |
| ISGF3G Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| ISGF3G Activity | | N/A |
| Tag | | ISGF3G Contains A 6x histidine tag |
| ISGF3G Formulation | | Liquid |
| ISGF3G Storage | | ;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant ISGF3G Products | | For pricing and availability Click Here >>> |
| ISGF3G family | | IRF family |
| ISGF3G Subcellular locations | | Cytoplasm. Nucleus. |
| ISGF3G FUNCTION According to UniProtKB Swiss Prot | | FUNCTION: Transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state. |
| ISGF3G Sequence | | DDBJ | EMBL | GenBank |
| ISGF3G 3D structure | | ModBase |
| ISGF3G interaction | | STRING |
| ISGF3G Proteomic | | PRIDE |
| ISGF3G Genome annotation | | Ensembl | GeneID | KEGG | UCSC |
| ISGF3G Organism specific | | CTD | MGI |
| ISGF3G Phylogenomics | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| ISGF3G Gene expression | | Bgee | ArrayExpress | Genevestigator |
| ISGF3G Family and domain | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |