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Mouse Complement component C8 alpha chain (aa 31-587)

C8a Swiss Prot#

Q8K182

C8a Protein names

Complement component C8 alpha chain (Complement component 8 subunit alpha)

C8a Gene names

C8a

Organism

Mouse

C8a Entry name

CO8A_MOUSE

C8a Codon optimized cDNA(gene) Clone

C8a Cat #

RPW0282

Tag

C8a contains A 6x histidine tag

C8a Formulation

Liquid

C8a Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

C8a Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant C8a Protein

C8a Cat #

PW0282

C8a Source

recombinant

C8a Applications

Western Blot, SDS-Page or may be used for other applications determined by user

C8a Purity

>90%, as determined by SDS-PAGE under reducing conditions

C8a Activity

N/A

Tag

C8a Contains A 6x histidine tag

C8a Formulation

Liquid

C8a Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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C8a family

Complement C6/C7/C8/C9 family

C8a Subcellular locations

Secreted. Cell membrane; Multi-pass membrane protein.

C8a FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C8A inserts into the target membrane, but does not form pores by itself (By similarity).

C8a Sequence

DDBJ

EMBL

GenBank

C8a 3D structure

ModBase

C8a interaction

STRING

C8a Proteomic

PRIDE

C8a Genome annotation

Ensembl

GeneID

KEGG

UCSC

C8a Organism specific

CTD

MGI

C8a Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

C8a Gene expression

Bgee

ArrayExpress

Genevestigator

C8a Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY