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Mouse Docking protein 1 (aa 1-482)

Dok Swiss Prot#

P97465

Dok Protein names

Docking protein 1 (Downstream of tyrosine kinase 1) (p62(dok))

Dok Gene names

Dok1 (Dok)

Organism

Mouse

Dok Entry name

DOK1_MOUSE

Dok Codon optimized cDNA(gene) Clone

Dok Cat #

RPW0256

Tag

Dok contains A 6x histidine tag

Dok Formulation

Liquid

Dok Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Dok Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Dok Protein

Dok Cat #

PW0256

Dok Source

recombinant

Dok Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Dok Purity

>90%, as determined by SDS-PAGE under reducing conditions

Dok Activity

N/A

Tag

Dok Contains A 6x histidine tag

Dok Formulation

Liquid

Dok Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Dok family

DOK family, Type A subfamily

Dok Subcellular locations

Cytoplasm.

Dok FUNCTION According to UniProtKB Swiss Prot

FUNCTION: DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3 (By similarity).

Dok Sequence

DDBJ

EMBL

GenBank

Dok 3D structure

ModBase

Dok interaction

STRING

Dok Proteomic

PRIDE

Dok Genome annotation

Ensembl

GeneID

KEGG

UCSC

Dok Organism specific

CTD

MGI

Dok Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Dok Gene expression

Bgee

ArrayExpress

Genevestigator

Dok Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY