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Mouse Serine threonine-protein kinase receptor R3 (aa 201-502)

Acvrlk1 Swiss Prot#

Q61288

Acvrlk1 Protein names

Serine/threonine-protein kinase receptor R3 (SKR3) (EC 2.7.11.30) (Activin receptor-like kinase 1) (ALK-1) (TGF-B superfamily receptor type I) (TSR-I)

Acvrlk1 Gene names

Acvrl1 (Acvrlk1) (Alk-1)

Organism

Mouse

Acvrlk1 Entry name

ACVL1_MOUSE

Acvrlk1 Codon optimized cDNA(gene) Clone

Acvrlk1 Cat #

RPW0255

Tag

Acvrlk1 contains A 6x histidine tag

Acvrlk1 Formulation

Liquid

Acvrlk1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Acvrlk1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Acvrlk1 Protein

Acvrlk1 Cat #

PW0255

Acvrlk1 Source

recombinant

Acvrlk1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Acvrlk1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Acvrlk1 Activity

N/A

Tag

Acvrlk1 Contains A 6x histidine tag

Acvrlk1 Formulation

Liquid

Acvrlk1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Acvrlk1 family

Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily

Acvrlk1 Subcellular locations

Membrane; Single-pass type I membrane protein.

Acvrlk1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for TGF-beta. May bind activin as well.

Acvrlk1 Sequence

DDBJ

EMBL

GenBank

Acvrlk1 3D structure

ModBase

Acvrlk1 interaction

STRING

Acvrlk1 Proteomic

PRIDE

Acvrlk1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Acvrlk1 Organism specific

CTD

MGI

Acvrlk1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Acvrlk1 Gene expression

Bgee

ArrayExpress

Genevestigator

Acvrlk1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY