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Mouse Leukosialin (aa 20-248)

Spn Swiss Prot#

P15702

Spn Protein names

Leukosialin (Leukocyte sialoglycoprotein) (Sialophorin) (Ly-48) (B-cell differentiation antigen LP-3) (CD antigen CD43)

Spn Gene names

Spn

Organism

Mouse

Spn Entry name

LEUK_MOUSE

Spn Codon optimized cDNA(gene) Clone

Spn Cat #

RPW0219

Tag

Spn contains A 6x histidine tag

Spn Formulation

Liquid

Spn Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Spn Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Spn Protein

Spn Cat #

PW0219

Spn Source

recombinant

Spn Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Spn Purity

>90%, as determined by SDS-PAGE under reducing conditions

Spn Activity

N/A

Tag

Spn Contains A 6x histidine tag

Spn Formulation

Liquid

Spn Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Spn family

-

Spn Subcellular locations

Membrane; Single-pass type I membrane protein.

Spn FUNCTION According to UniProtKB Swiss Prot

FUNCTION: One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter receptor for SN/Siglec-1. During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response.

Spn Sequence

DDBJ

EMBL

GenBank

Spn 3D structure

ModBase

Spn interaction

STRING

Spn Proteomic

PRIDE

Spn Genome annotation

Ensembl

GeneID

KEGG

UCSC

Spn Organism specific

CTD

MGI

Spn Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Spn Gene expression

Bgee

ArrayExpress

Genevestigator

Spn Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY