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Mouse Proheparin-binding EGF-like growth factor (aa 24-106)

Dtr Swiss Prot#

Q06186

Dtr Protein names

Proheparin-binding EGF-like growth factor [Cleaved into: Heparin-binding EGF-like growth factor (HB-EGF) (HBEGF)]

Dtr Gene names

Hbegf (Dtr) (Hegfl)

Organism

Mouse

Dtr Entry name

HBEGF_MOUSE

Dtr Codon optimized cDNA(gene) Clone

Dtr Cat #

RPW0165

Tag

Dtr contains A 6x histidine tag

Dtr Formulation

Liquid

Dtr Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Dtr Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Dtr Protein

Dtr Cat #

PW0165

Dtr Source

recombinant

Dtr Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Dtr Purity

>90%, as determined by SDS-PAGE under reducing conditions

Dtr Activity

N/A

Tag

Dtr Contains A 6x histidine tag

Dtr Formulation

Liquid

Dtr Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Dtr family

-

Dtr Subcellular locations

Secreted > extracellular space. Cell membrane; Single-pass type I membrane protein.

Dtr FUNCTION According to UniProtKB Swiss Prot

FUNCTION: May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts and smooth muscle but not endothelial cells. It is able to bind EGF receptors with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF.

Dtr Sequence

DDBJ

EMBL

GenBank

Dtr 3D structure

ModBase

Dtr interaction

STRING

Dtr Proteomic

PRIDE

Dtr Genome annotation

Ensembl

GeneID

KEGG

UCSC

Dtr Organism specific

CTD

MGI

Dtr Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Dtr Gene expression

Bgee

ArrayExpress

Genevestigator

Dtr Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY