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Human ATP-binding cassette sub-family E member 1 (aa 1-599)

RLI Swiss Prot#

P61221

RLI Protein names

ATP-binding cassette sub-family E member 1 (RNase L inhibitor) (Ribonuclease 4 inhibitor) (RNS4I) (2'-5'-oligoadenylate-binding protein) (HuHP68)

RLI Gene names

ABCE1 (RLI) (RNASEL1) (RNASELI) (RNS4I) (OK/SW-cl.40)

Organism

Human

RLI Entry name

ABCE1_HUMAN

RLI Codon optimized cDNA(gene) Clone

RLI Cat #

RPW0133

Tag

RLI contains A 6x histidine tag

RLI Formulation

Liquid

RLI Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

RLI Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant RLI Protein

RLI Cat #

PW0133

RLI Source

recombinant

RLI Applications

Western Blot, SDS-Page or may be used for other applications determined by user

RLI Purity

>90%, as determined by SDS-PAGE under reducing conditions

RLI Activity

N/A

Tag

RLI Contains A 6x histidine tag

RLI Formulation

Liquid

RLI Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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RLI family

ABC transporter superfamily, ABCE family

RLI Subcellular locations

Cytoplasm. Mitochondrion.

RLI FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Antagonizes the binding of 2-5A (5'-phosphorylated 2',5'-linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in the regulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway. May act as a chaperone for post-translational events during HIV-1 capsid assembly.

RLI Sequence

DDBJ

EMBL

GenBank

RLI 3D structure

ModBase

RLI interaction

STRING

RLI Proteomic

PRIDE

RLI Genome annotation

Ensembl

GeneID

KEGG

UCSC

RLI Organism specific

CTD

MGI

RLI Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

RLI Gene expression

Bgee

ArrayExpress

Genevestigator

RLI Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY