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Human Syntaxin-binding protein 1 (aa 1-594)

UNC18A Swiss Prot#

P61764

UNC18A Protein names

Syntaxin-binding protein 1 (Unc-18 homolog) (Unc-18-1) (Unc-18A) (N-Sec1) (p67)

UNC18A Gene names

STXBP1 (UNC18A)

Organism

Human

UNC18A Entry name

STXB1_HUMAN

UNC18A Codon optimized cDNA(gene) Clone

UNC18A Cat #

RPW0132

Tag

UNC18A contains A 6x histidine tag

UNC18A Formulation

Liquid

UNC18A Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

UNC18A Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant UNC18A Protein

UNC18A Cat #

PW0132

UNC18A Source

recombinant

UNC18A Applications

Western Blot, SDS-Page or may be used for other applications determined by user

UNC18A Purity

>90%, as determined by SDS-PAGE under reducing conditions

UNC18A Activity

N/A

Tag

UNC18A Contains A 6x histidine tag

UNC18A Formulation

Liquid

UNC18A Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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UNC18A family

STXBP/unc-18/SEC1 family

UNC18A Subcellular locations

Cytoplasm. Membrane; Peripheral membrane protein.

UNC18A FUNCTION According to UniProtKB Swiss Prot

FUNCTION: May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions.

UNC18A Sequence

DDBJ

EMBL

GenBank

UNC18A 3D structure

ModBase

UNC18A interaction

STRING

UNC18A Proteomic

PRIDE

UNC18A Genome annotation

Ensembl

GeneID

KEGG

UCSC

UNC18A Organism specific

CTD

MGI

UNC18A Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

UNC18A Gene expression

Bgee

ArrayExpress

Genevestigator

UNC18A Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY