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Human Tripartite motif-containing protein 5 (aa 1-493)

RNF88 Swiss Prot#

Q9C035

RNF88 Protein names

Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88)

RNF88 Gene names

TRIM5 (RNF88)

Organism

Human

RNF88 Entry name

TRIM5_HUMAN

RNF88 Codon optimized cDNA(gene) Clone

RNF88 Cat #

RPW0113

Tag

RNF88 contains A 6x histidine tag

RNF88 Formulation

Liquid

RNF88 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

RNF88 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant RNF88 Protein

RNF88 Cat #

PW0113

RNF88 Source

recombinant

RNF88 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

RNF88 Purity

>90%, as determined by SDS-PAGE under reducing conditions

RNF88 Activity

N/A

Tag

RNF88 Contains A 6x histidine tag

RNF88 Formulation

Liquid

RNF88 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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RNF88 family

TRIM/RBCC family

RNF88 Subcellular locations

Cytoplasm > P-body.

RNF88 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Isoform Alpha is a retrovirus restriction factor, which mediates species-specific, early block to retrovirus infection. Targets retroviral capsid soon after entry into the cell, and prevents reverse transcription of the virus RNA genome. Isoform Alpha trimers may make multiple contacts with the hexameric lattice of CA proteins which constitute the surface of retrovirion core, and somehow inactivate the virus. Restricts efficiently infection by N-MLV, but not HIV-1. May have E3 ubiquitin-protein ligase activity.

RNF88 Sequence

DDBJ

EMBL

GenBank

RNF88 3D structure

ModBase

RNF88 interaction

STRING

RNF88 Proteomic

PRIDE

RNF88 Genome annotation

Ensembl

GeneID

KEGG

UCSC

RNF88 Organism specific

CTD

MGI

RNF88 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

RNF88 Gene expression

Bgee

ArrayExpress

Genevestigator

RNF88 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY