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Human Dipeptidyl-peptidase 1 (aa 1-463)
CPPI Swiss Prot#
P53634
CPPI Protein names
Dipeptidyl-peptidase 1 (EC 3.4.14.1) (Dipeptidyl-peptidase I) (DPP-I) (DPPI) (Cathepsin C) (Cathepsin J) (Dipeptidyl transferase) [Cleaved into: Dipeptidyl-peptidase 1 exclusion domain chain (Dipeptidyl-peptidase I exclusion domain chain) Dipeptidyl-peptidase 1 heavy chain (Dipeptidyl-peptidase I heavy chain) Dipeptidyl-peptidase 1 light chain (Dipeptidyl-peptidase I light chain)]
CPPI Gene names
CTSC (CPPI)
Organism
Human
CPPI Entry name
CATC_HUMAN
CPPI Codon optimized cDNA(gene) Clone
CPPI Cat #
RPW0107
Tag
CPPI contains A 6x histidine tag
CPPI Formulation
Liquid
CPPI Storage
Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
CPPI Applications
Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant CPPI Protein
CPPI Cat #
PW0107
CPPI Source
recombinant
CPPI Applications
Western Blot, SDS-Page or may be used for other applications determined by user
CPPI Purity
>90%, as determined by SDS-PAGE under reducing conditions
CPPI Activity
N/A
Tag
CPPI Contains A 6x histidine tag
CPPI Formulation
Liquid
CPPI Storage
;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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CPPI family
Peptidase C1 family
CPPI Subcellular locations
Lysosome.
CPPI FUNCTION According to UniProtKB Swiss Prot
FUNCTION: Thiol protease. Has dipeptidylpeptidase activity. Active against a broad range of dipeptide substrates composed of both polar and hydrophobic amino acids. Proline cannot occupy the P1 position and arginine cannot occupy the P2 position of the substrate. Can act as both an exopeptidase and endopeptidase. Activates serine proteases such as elastase, cathepsin G and granzymes A and B. Can also activate neuraminidase and factor XIII.
CPPI Sequence
DDBJ EMBL GenBank
CPPI 3D structure
ModBase
CPPI interaction
STRING
CPPI Proteomic
PRIDE
CPPI Genome annotation
Ensembl GeneID KEGG UCSC
CPPI Organism specific
CTD MGI
CPPI Phylogenomics
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
CPPI Gene expression
Bgee ArrayExpress Genevestigator
CPPI Family and domain
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY