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| Human Dipeptidyl-peptidase 1 (aa 1-463) |
| CPPI Swiss Prot# | | P53634 |
| CPPI Protein names | | Dipeptidyl-peptidase 1 (EC 3.4.14.1) (Dipeptidyl-peptidase I) (DPP-I) (DPPI) (Cathepsin C) (Cathepsin J) (Dipeptidyl transferase) [Cleaved into: Dipeptidyl-peptidase 1 exclusion domain chain (Dipeptidyl-peptidase I exclusion domain chain) Dipeptidyl-peptidase 1 heavy chain (Dipeptidyl-peptidase I heavy chain) Dipeptidyl-peptidase 1 light chain (Dipeptidyl-peptidase I light chain)] |
| CPPI Gene names | | CTSC (CPPI) |
| Organism | | Human |
| CPPI Entry name | | CATC_HUMAN |
| CPPI Codon optimized cDNA(gene) Clone |
| CPPI Cat # | | RPW0107 |
| Tag | | CPPI contains A 6x histidine tag |
| CPPI Formulation | | Liquid |
| CPPI Storage | | Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| CPPI Applications | | Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function. |
| Recombinant CPPI Protein |
| CPPI Cat # | | PW0107 |
| CPPI Source | | recombinant |
| CPPI Applications | | Western Blot, SDS-Page or may be used for other applications determined by user |
| CPPI Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| CPPI Activity | | N/A |
| Tag | | CPPI Contains A 6x histidine tag |
| CPPI Formulation | | Liquid |
| CPPI Storage | | ;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant CPPI Products | | For pricing and availability Click Here >>> |
| CPPI family | | Peptidase C1 family |
| CPPI Subcellular locations | | Lysosome. |
| CPPI FUNCTION According to UniProtKB Swiss Prot | | FUNCTION: Thiol protease. Has dipeptidylpeptidase activity. Active against a broad range of dipeptide substrates composed of both polar and hydrophobic amino acids. Proline cannot occupy the P1 position and arginine cannot occupy the P2 position of the substrate. Can act as both an exopeptidase and endopeptidase. Activates serine proteases such as elastase, cathepsin G and granzymes A and B. Can also activate neuraminidase and factor XIII. |
| CPPI Sequence | | DDBJ | EMBL | GenBank |
| CPPI 3D structure | | ModBase |
| CPPI interaction | | STRING |
| CPPI Proteomic | | PRIDE |
| CPPI Genome annotation | | Ensembl | GeneID | KEGG | UCSC |
| CPPI Organism specific | | CTD | MGI |
| CPPI Phylogenomics | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| CPPI Gene expression | | Bgee | ArrayExpress | Genevestigator |
| CPPI Family and domain | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |