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Human Bactericidal permeability-increasing protein (aa 32-487)

BPI Swiss Prot#

P17213

BPI Protein names

Bactericidal permeability-increasing protein (BPI) (CAP 57)

BPI Gene names

BPI

Organism

Human

BPI Entry name

BPI_HUMAN

BPI Codon optimized cDNA(gene) Clone

BPI Cat #

RPW0104

Tag

BPI contains A 6x histidine tag

BPI Formulation

Liquid

BPI Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

BPI Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant BPI Protein

BPI Cat #

PW0104

BPI Source

recombinant

BPI Applications

Western Blot, SDS-Page or may be used for other applications determined by user

BPI Purity

>90%, as determined by SDS-PAGE under reducing conditions

BPI Activity

N/A

Tag

BPI Contains A 6x histidine tag

BPI Formulation

Liquid

BPI Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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BPI family

BPI/LBP/Plunc superfamily, BPI/LBP family

BPI Subcellular locations

Secreted. Cytoplasmic granule membrane.

BPI FUNCTION According to UniProtKB Swiss Prot

FUNCTION: The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. Has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa.

BPI Sequence

DDBJ

EMBL

GenBank

BPI 3D structure

ModBase

BPI interaction

STRING

BPI Proteomic

PRIDE

BPI Genome annotation

Ensembl

GeneID

KEGG

UCSC

BPI Organism specific

CTD

MGI

BPI Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

BPI Gene expression

Bgee

ArrayExpress

Genevestigator

BPI Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY