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Human Runt-related transcription factor 3 (aa 1-415)
AML2 Swiss Prot#
Q13761
AML2 Protein names
Runt-related transcription factor 3 (Core-binding factor subunit alpha-3) (CBF-alpha-3) (Acute myeloid leukemia 2 protein) (Oncogene AML-2) (Polyomavirus enhancer-binding protein 2 alpha C subunit) (PEBP2-alpha C) (PEA2-alpha C) (SL3-3 enhancer factor 1 alpha C subunit) (SL3/AKV core-binding factor alpha C subunit)
AML2 Gene names
RUNX3 (AML2) (CBFA3) (PEBP2A3)
Organism
Human
AML2 Entry name
RUNX3_HUMAN
AML2 Codon optimized cDNA(gene) Clone
AML2 Cat #
RPW0091
Tag
AML2 contains A 6x histidine tag
AML2 Formulation
Liquid
AML2 Storage
Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
AML2 Applications
Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant AML2 Protein
AML2 Cat #
PW0091
AML2 Source
recombinant
AML2 Applications
Western Blot, SDS-Page or may be used for other applications determined by user
AML2 Purity
>90%, as determined by SDS-PAGE under reducing conditions
AML2 Activity
N/A
Tag
AML2 Contains A 6x histidine tag
AML2 Formulation
Liquid
AML2 Storage
;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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AML2 family
-
AML2 Subcellular locations
Nucleus. Cytoplasm.
AML2 FUNCTION According to UniProtKB Swiss Prot
FUNCTION: CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, lck, IL-3 and GM-CSF promoters.
AML2 Sequence
DDBJ EMBL GenBank
AML2 3D structure
ModBase
AML2 interaction
STRING
AML2 Proteomic
PRIDE
AML2 Genome annotation
Ensembl GeneID KEGG UCSC
AML2 Organism specific
CTD MGI
AML2 Phylogenomics
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
AML2 Gene expression
Bgee ArrayExpress Genevestigator
AML2 Family and domain
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY