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Human DNA dC->dU-editing enzyme APOBEC-3F (aa 1-373)

APOBEC3F Swiss Prot#

Q8IUX4

APOBEC3F Protein names

DNA dC->dU-editing enzyme APOBEC-3F (EC 3.5.4.-) (Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3F)

APOBEC3F Gene names

APOBEC3F

Organism

Human

APOBEC3F Entry name

ABC3F_HUMAN

APOBEC3F Codon optimized cDNA(gene) Clone

APOBEC3F Cat #

RPW0084

Tag

APOBEC3F contains A 6x histidine tag

APOBEC3F Formulation

Liquid

APOBEC3F Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

APOBEC3F Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant APOBEC3F Protein

APOBEC3F Cat #

PW0084

APOBEC3F Source

recombinant

APOBEC3F Applications

Western Blot, SDS-Page or may be used for other applications determined by user

APOBEC3F Purity

>90%, as determined by SDS-PAGE under reducing conditions

APOBEC3F Activity

N/A

Tag

APOBEC3F Contains A 6x histidine tag

APOBEC3F Formulation

Liquid

APOBEC3F Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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APOBEC3F family

Cytidine and deoxycytidylate deaminase family

APOBEC3F Subcellular locations

-

APOBEC3F FUNCTION According to UniProtKB Swiss Prot

FUNCTION: After being packaged into HIV-1 virions, blocks productive infection by massively editing dC residues to dU on the DNA minus strand during reverse transcription. The editing of the minus strand DNA of HIV-1 during reverse transcription leads to G-to-A transitions in the plus strand. The inhibition of viral replication is either due to the degradation of the minus strand before its integration or to the lethality of the hypermutations.

APOBEC3F Sequence

DDBJ

EMBL

GenBank

APOBEC3F 3D structure

ModBase

APOBEC3F interaction

STRING

APOBEC3F Proteomic

PRIDE

APOBEC3F Genome annotation

Ensembl

GeneID

KEGG

UCSC

APOBEC3F Organism specific

CTD

MGI

APOBEC3F Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

APOBEC3F Gene expression

Bgee

ArrayExpress

Genevestigator

APOBEC3F Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY