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Human Adenosine deaminase (aa 2-363)

ADA Swiss Prot#

P00813

ADA Protein names

Adenosine deaminase (EC 3.5.4.4) (Adenosine aminohydrolase)

ADA Gene names

ADA

Organism

Human

ADA Entry name

ADA_HUMAN

ADA Codon optimized cDNA(gene) Clone

ADA Cat #

RPW0081

Tag

ADA contains A 6x histidine tag

ADA Formulation

Liquid

ADA Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

ADA Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant ADA Protein

ADA Cat #

PW0081

ADA Source

recombinant

ADA Applications

Western Blot, SDS-Page or may be used for other applications determined by user

ADA Purity

>90%, as determined by SDS-PAGE under reducing conditions

ADA Activity

N/A

Tag

ADA Contains A 6x histidine tag

ADA Formulation

Liquid

ADA Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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ADA family

Adenosine and AMP deaminases family

ADA Subcellular locations

Cell membrane; Peripheral membrane protein; Extracellular side. Cell junction. Cytoplasmic vesicle lumen. Cytoplasm.

ADA FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a positive regulator of T-cell coactivation, by binding DPP4. Its interaction with DPP4 regulates lymphocyte-epithelial cell adhesion.

ADA Sequence

DDBJ

EMBL

GenBank

ADA 3D structure

ModBase

ADA interaction

STRING

ADA Proteomic

PRIDE

ADA Genome annotation

Ensembl

GeneID

KEGG

UCSC

ADA Organism specific

CTD

MGI

ADA Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

ADA Gene expression

Bgee

ArrayExpress

Genevestigator

ADA Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY