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Human Hepatitis A virus cellular receptor 2 (aa 22-202)

TIM3 Swiss Prot#

Q8TDQ0

TIM3 Protein names

Hepatitis A virus cellular receptor 2 (HAVcr-2) (T-cell immunoglobulin and mucin domain-containing protein 3) (TIMD-3) (T-Cell membrane protein 3) (TIM-3)

TIM3 Gene names

HAVCR2 (TIM3) (TIMD3)

Organism

Human

TIM3 Entry name

TIMD3_HUMAN

TIM3 Codon optimized cDNA(gene) Clone

TIM3 Cat #

RPW0056

Tag

TIM3 contains A 6x histidine tag

TIM3 Formulation

Liquid

TIM3 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

TIM3 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant TIM3 Protein

TIM3 Cat #

PW0056

TIM3 Source

recombinant

TIM3 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

TIM3 Purity

>90%, as determined by SDS-PAGE under reducing conditions

TIM3 Activity

N/A

Tag

TIM3 Contains A 6x histidine tag

TIM3 Formulation

Liquid

TIM3 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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TIM3 family

Immunoglobulin superfamily, TIM family

TIM3 Subcellular locations

Membrane; Single-pass type I membrane protein.

TIM3 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Regulates macrophage activation. Inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. May be also involved in T-cell homing. Receptor for LGALS9.

TIM3 Sequence

DDBJ

EMBL

GenBank

TIM3 3D structure

ModBase

TIM3 interaction

STRING

TIM3 Proteomic

PRIDE

TIM3 Genome annotation

Ensembl

GeneID

KEGG

UCSC

TIM3 Organism specific

CTD

MGI

TIM3 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

TIM3 Gene expression

Bgee

ArrayExpress

Genevestigator

TIM3 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY