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Human Cation-dependent mannose-6-phosphate receptor (aa 27-277)

MPR46 Swiss Prot#

P20645

MPR46 Protein names

Cation-dependent mannose-6-phosphate receptor (CD Man-6-P receptor) (CD-MPR) (46 kDa mannose 6-phosphate receptor) (MPR 46)

MPR46 Gene names

M6PR (MPR46) (MPRD)

Organism

Human

MPR46 Entry name

MPRD_HUMAN

MPR46 Codon optimized cDNA(gene) Clone

MPR46 Cat #

RPW0051

Tag

MPR46 contains A 6x histidine tag

MPR46 Formulation

Liquid

MPR46 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

MPR46 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant MPR46 Protein

MPR46 Cat #

PW0051

MPR46 Source

recombinant

MPR46 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

MPR46 Purity

>90%, as determined by SDS-PAGE under reducing conditions

MPR46 Activity

N/A

Tag

MPR46 Contains A 6x histidine tag

MPR46 Formulation

Liquid

MPR46 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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MPR46 family

-

MPR46 Subcellular locations

Lysosome membrane; Single-pass type I membrane protein.

MPR46 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex.

MPR46 Sequence

DDBJ

EMBL

GenBank

MPR46 3D structure

ModBase

MPR46 interaction

STRING

MPR46 Proteomic

PRIDE

MPR46 Genome annotation

Ensembl

GeneID

KEGG

UCSC

MPR46 Organism specific

CTD

MGI

MPR46 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

MPR46 Gene expression

Bgee

ArrayExpress

Genevestigator

MPR46 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY