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Human SH2 domain-containing protein 1A (aa 1-128)

DSHP Swiss Prot#

O60880

DSHP Protein names

SH2 domain-containing protein 1A (Signaling lymphocytic activation molecule-associated protein) (SLAM-associated protein) (T-cell signal transduction molecule SAP) (Duncan disease SH2-protein)

DSHP Gene names

SH2D1A (DSHP) (SAP)

Organism

Human

DSHP Entry name

SH21A_HUMAN

DSHP Codon optimized cDNA(gene) Clone

DSHP Cat #

RPW0001

Tag

DSHP contains A 6x histidine tag

DSHP Formulation

Liquid

DSHP Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

DSHP Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant DSHP Protein

DSHP Cat #

PW0001

DSHP Source

recombinant

DSHP Applications

Western Blot, SDS-Page or may be used for other applications determined by user

DSHP Purity

>90%, as determined by SDS-PAGE under reducing conditions

DSHP Activity

N/A

Tag

DSHP Contains A 6x histidine tag

DSHP Formulation

Liquid

DSHP Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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DSHP family

-

DSHP Subcellular locations

Cytoplasm.

DSHP FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Inhibitor of the SLAM self-association. Acts by blocking recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to a docking site in the SLAM cytoplasmic region. Mediates interaction between FYN and SLAMF1.

DSHP Sequence

DDBJ

EMBL

GenBank

DSHP 3D structure

ModBase

DSHP interaction

STRING

DSHP Proteomic

PRIDE

DSHP Genome annotation

Ensembl

GeneID

KEGG

UCSC

DSHP Organism specific

CTD

MGI

DSHP Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

DSHP Gene expression

Bgee

ArrayExpress

Genevestigator

DSHP Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY