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Human Proto-oncogene tyrosine-protein kinase Fyn (aa 271–524)

FYN Swiss Prot#

P06241

FYN Protein names

Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene Syn) (SLK)

FYN Gene names

FYN

Organism

Human

FYN Entry name

FYN_HUMAN

FYN Codon optimized cDNA(gene) Clone

FYN Cat #

RPE0822

Tag

FYN contains A 6x histidine tag

FYN Formulation

Liquid

FYN Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

FYN Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant FYN Protein

FYN Cat #

PE0822

FYN Source

recombinant

FYN Applications

Western Blot, SDS-Page or may be used for other applications determined by user

FYN Purity

>90%, as determined by SDS-PAGE under reducing conditions

FYN Activity

N/A

Tag

FYN Contains A 6x histidine tag

FYN Formulation

Liquid

FYN Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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FYN family

Protein kinase superfamily, Tyr protein kinase family, SRC subfamily

FYN Subcellular locations

Cell membrane.

FYN FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Tyrosine-protein kinase implicated in the control of cell growth. Plays a role in the regulation of intracellular calcium levels, with isoform 2 showing the greater ability to mobilize cytoplasmic calcium in comparison to isoform 1. Required in brain development and mature brain function with important roles in the regulation of axon growth, axon guidance, and neurite extension. Blocks axon outgrowth and attraction induced by NTN1 by phosphorylating its receptor DDC. Phosphorylates RUNX3.

FYN Sequence

DDBJ

EMBL

GenBank

FYN 3D structure

ModBase

FYN interaction

STRING

FYN Proteomic

PRIDE

FYN Genome annotation

Ensembl

GeneID

KEGG

UCSC

FYN Organism specific

CTD

MGI

FYN Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

FYN Gene expression

Bgee

ArrayExpress

Genevestigator

FYN Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY