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Human Tyrosinase (aa 19–529)

TYR Swiss Prot#

P14679

TYR Protein names

Tyrosinase (EC 1.14.18.1) (Monophenol monooxygenase) (Tumor rejection antigen AB) (SK29-AB) (LB24-AB)

TYR Gene names

TYR

Organism

Human

TYR Entry name

TYRO_HUMAN

TYR Codon optimized cDNA(gene) Clone

TYR Cat #

RPE0813

Tag

TYR contains A 6x histidine tag

TYR Formulation

Liquid

TYR Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

TYR Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant TYR Protein

TYR Cat #

PE0813

TYR Source

recombinant

TYR Applications

Western Blot, SDS-Page or may be used for other applications determined by user

TYR Purity

>90%, as determined by SDS-PAGE under reducing conditions

TYR Activity

N/A

Tag

TYR Contains A 6x histidine tag

TYR Formulation

Liquid

TYR Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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TYR family

Tyrosinase family

TYR Subcellular locations

Melanosome membrane; Single-pass type I membrane protein.

TYR FUNCTION According to UniProtKB Swiss Prot

FUNCTION: This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the rate-limiting conversions of tyrosine to DOPA, DOPA to DOPA-quinone and possibly 5,6-dihydroxyindole to indole-5,6 quinone.

TYR Sequence

DDBJ

EMBL

GenBank

TYR 3D structure

ModBase

TYR interaction

STRING

TYR Proteomic

PRIDE

TYR Genome annotation

Ensembl

GeneID

KEGG

UCSC

TYR Organism specific

CTD

MGI

TYR Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

TYR Gene expression

Bgee

ArrayExpress

Genevestigator

TYR Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY